Cytokeratin-7 |
Cytokeratin-18 |
FUC-T-IV |
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abbr. and approved gene symbol: KRT15 [keratin-15]; abbr. also K15, CK15. Cytokeratin-15 belongs to the family of structurally related keratins that form intermediate filaments in epithelial cells (for overview see also: Bose et al, 2013). The C8/144B antigen (named after a monoclonal antibody of the same name) has been shown to detect cytokeratin-15 (Lyle et al, 1998). The cytokeratin-15 gene has been characterized by Leube et al (1988) and Whittock et al (2000). Waseem A et al (1999) have shown that cytokeratin-15 is expressed primarily in the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Cytokeratin-15 in normal hair follicles is virtually absent from hair bulbs, but it is expressed by a subset of
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