lineage markers
[lin(-), lin(low), lineage marker, lin(+), lineage(-), lineage(+)]
Lineage markers are cell surface antigens that can be used for immunophenotyping cells of a particular developmental cell lineage.
Specifically, a set of 'Lin' antigens comprising CD2, CD3, CD4, CD5, CD8, NK1.1, B220, TER-119, Gr-1 is used to identify mature murine blood cells. Cells that do not express these marker antigens, or express them at very low levels, are said to be lineage marker negative [lin(-)]. The monoclonal antibody cocktails directed against these lineage markers are used to remove cells
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