mechanocytes |
mechano growth factor E peptide |
major centromere autoantigen B |
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abbr. MGF (a term with multiple meanings). This factor is a splice variant of IGF-1 produced by active muscle. MGF is derived from the IGF-1 gene by alternative splicing but it has different exons to the liver isoforms. MGF is structurally identical to rodent IGF-1 Eb, identified originally as an isoform of hepatic IGF-1 (Roberts et al, 1987). MGF has a 52 base insert (49 bp insert in humans) in the E domain, which alters the reading frame of the 3' end. In humans, the corresponding isoform is IGF-1 Ec.
MGF is a growth/repair factor produced by
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