Methionyl aminopeptidase-2 |
Met-His-Ser-Pro-Gly-Ala-Asp |
Multiple EGF-like domains protein 12 |
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abbr. and approved gene symbol: MARS; abbr. also: MRS, MetRS. The enzyme (EC6.1.1.10 in the enzyme nomenclature catalogue) is known also as Methionine-tRNA ligase. The human gene has been cloned by Lage and Dietel (1996)
Role as moonlighting protein
Apart from its essential role in initiating translation by transferring Methionine to the Met initiator tRNA, methionyl-tRNA synthetase has other functions and thus can be regarded as a member of a growing group of proteins referred to as moonlighting proteins. The enzyme contains a distinct
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