patched-1 |
patched homolog 1 |
CD3z |
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approved gene symbol: PTCH2 [patched homolog 2], abbr. also: PTC2 is a second ortholog of the Drosophila melanogaster patched gene (abbr. ptc; gene: CG2411). The human gene has been identified by Smyth et al (1999) who reported a possible role as tumor suppressor in basal cell carcinoma and medulloblastoma. The mouse gene has been cloned by Motoyama et al (1998). Carpenter et al (1998) have reported that PTCH2 binds all three Hedgehog family members (SHH, DHH, IHH
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