periostin-like factor |
peripheral blood insulin-producing cells |
MMPL1 |
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[peripheral antigen-expressing cell]
This general term has been used to refer to thymic medullary epithelial cells (see, for example: Hanahan et al, 1998; Zheng et al, 2004). These cells express peripheral antigens via a mechanism depending on AIRE [autoimmune regulator] and essentially contribute to the establishment of self-tolerance by the deletion of self-reactive T-cells and the generation of regulatory T-cells (Anderson and Takahama, 2012). Zhang et al (2004) have reported that bone marrow-derived peripheral antigen-expressing cells exist in both central and secondary lymphoid organs and that the expression of peripheral antigens in these cells
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