tabimmunregulin 12 |
Tabinhibitin 1 |
protein tyrosine phosphatase receptor type Ca |
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Tabimmunregulins are a family of 12 peptides from the salivary gland of the horsefly Tabanus yao (Diptera, Tabanidae) (Xu et al, 2008). These peptides are encoded in the C-terminal end of a longer precursor protein.
At least two of these peptides, tabimmunregulin 1 (GGVSGVSDFEPIEVFGEDYDSDEADEDGKG), and tabimmunregulin 12 (GGVSGVGDYKPIVVFGKSFNQFEAAEGAKG have been shown to possess immunosuppressive activities, increasing the production of IL10 in mouse splenocytes and decreasing the secretion of pro-inflammatory IFN-gamma in response to LPS. The peptides
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