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transcription initiation RNAs

[transcription initiation RNA]

abbr. tiRNAs (an abbreviation with multiple meanings). These RNAs are conserved small non-coding RNAs of 18 nucleotides, sometimes being referred to as promoter-associated RNAs, (also: promoter-associated ncRNAs, abbr. pncRNAs) are found in the nuclei of metazoan cells but are absent in fungi and plants. Transcription initiation RNAs are generated from regions immediately downstream of RNA polymerase II transcription start sites of genes. For other RNAs targeting promoter regions see also: Antigene RNAs.

The expression of promoter-associated RNAs is correlated intimately with gene expression, RNA polymerase II binding, and ... ... ... ... ... Subscribe to continue reading! ... ...

 

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