tuft cells

Tuft cells, which are being referred to also as brush cells, have been identified first in the rat trachea (Rhodin and Dalhamn, 1956) and mouse gastrointestinal tract (Jarvi and Keyrilainen, 1956) and also in the gastrointestinal mucosa of the rat (Isomäki et al, 1973) and humans (Gerbe et al, 2011). Tuft cells are a rare type of intestinal epithelial cells of largely unknown function (for overview see: Gerbe F et al, 2012). Gastrointestinal tuft cells have been reported to express several members of the taste transduction pathway, suggesting a function of this cell type in chemoreception (for discussion see: Finger and Kinnamon, 2011).

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Entry last modified: May 2021