vIL17 |
Villin |
Growth regulated oncogene-beta |
||
[viral IL18 binding protein] This protein is shown to be secreted into the conditioned medium of cells infected with vaccinia (vaccinia virus C12L gene; Born et al, 2000), ectromelia and cowpox viruses (Calderara et al, 2001; Smith et al, 2000). The ectromelia virus protein (referred to as E19) blocks NF-kappa-B activation and induction of IFN-gamma in response to IL18 (Smith et al, 2000). The vaccinia virus vIL18BP has been shown to inactivate IL18 and inhibits NK-cell responses (Born et al, 2000). Symons et al (2002) have reported that this protein promotes virus virulence.
For other viral proteins binding to IL18 see also: ectromelia poxvirus p13
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |