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vasonatrin peptide

abbr. VNP (a term with multiple meanings). This synthetic peptide of 27 amino acids (Wei et al, 1993) possesses the 22 amino acid structure of the cardiovascular selective peptide CNP [C-type natriuretic peptide] and the 5 amino acid carboxyterminus of ANF [Atrial natriuretic factor]. The peptide combines the venodilating actions of CNP, the natriuretic actions of ANF, and unique arterial vasodilating actions not associated with either ANF or CNP. It down-regulates CNP receptor expression in cardiomyocytes and fibroblasts (Lu et al, 2004). VNP ... ... ... ... ... Subscribe to continue reading! ... ...

 

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