Proliferin-4 |
proline- and glutamine-rich protein |
KREMEN |
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abbr. PRP (a term with multiple meanings). also abbr. PLF-RP. This secreted protein / hormone, identified by (Linzer and Nathans, 1985), is related to the placental protein Proliferin (see also: MRP/PLF). Soares et al (2007) have proposed the designation Prl7d1 [prolactin family 7 subfamily D member 1] for this protein.
Proliferin-related protein mRNA is expressed at high levels in the fetal part of the placenta. Peak levels are seen at day 12 of gestation and after that levels decrease gradually until term. Yamaguchi et al (1995, 1994) have shown that proliferin-related protein secretion by murine placental cells is affected by cAMP levels but not by
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