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Cytokines & Cells Online Pathfinder Encyclopaedia

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BB1

This term has been used in several different ways.


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(-1-) B-lymphoblast antigen-1

This antigen is detected by a monoclonal antibody on human and nonhuman primate B-lymphoblastoid cell lines, EBV-activated B-cell blasts, most Burkitt's lymphomas, and Ia(+) B-lymphoblast-like myelomas (Yokochi et al, 1982). Freeman et al (1998) have reported that the BB1 monoclonal antibody recognizes both B7-1 (CD80) and an epitope on the cell surface antigen CD74.

For additional information on CD antigens see also: CD antigens MiniCOPE Dictionary.


ENTRY COMPLETED

REFERENCES: Freeman GJ et al The BB1 monoclonal antibody recognizes both cell surface CD74 (MHC class II-associated invariant chain) as well as B7-1 (CD80), resolving the question regarding a third CD28/CTLA-4 counterreceptor. Journal of Immunology 161: 2708-2715 (1998); Yokochi T et al B lymphoblast antigen (BB-1) expressed on Epstein-Barr virus-activated B cell blasts, B lymphoblastoid cell lines, and Burkitt's lymphomas. Journal of Immunology 128(2): 823-827 (1982)


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(-2-) see: basogranulin


ENTRY COMPLETED

BB1

The following COPE entries contain this entry term or one of its hypertext synonyms:

astrocytes, B7, Basogranulin, basophils, B-cells, Beta-cells, B-lymphoblast antigen-1, Bombesin, CD28, CD74, CD80, CD antigens MiniCOPE Dictionary, cholangiocytes, colonocytes, dendritic cells, endometrial cells, endothelial cells, enterocytes, fibroblasts, keratinocytes, keratocytes, Kupffer cells, Langerhans cells, Liver sinusoidal endothelial cells, macrophages, melanoma cells, microglial cells, monocytes, multiple myeloma cells, osteoblasts, pneumocytes, podocytes, Reed-Sternberg cells, T-cells, thymic epithelial cells, thyrocytes.

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