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BIM

[BCL2 interacting mediator of cell death] This protein was identified by virtue of its ability to bind to BCL2. The approved gene symbol is BCL2L11 [BCL2-like-11].

The protein is one of the BH3-only proteins, containing a single BCL2 homology domain BH3. BIM is the same as BAM, and BOD.

Three BIM isoforms, BIM-S (short), BIM-L (long), and BIM-EL (extra long), have been described. All isoforms induce cell death by apoptosis. Mami et al (2001) have described six other alternative splice forms of human BIM, ... ... ... ... ... Subscribe to continue reading! ... ...

 

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