C-peptide

also: Proinsulin C-Peptide [proinsulin connecting peptide] or Insulin C-Peptide [insulin connecting peptide]. This peptide with the sequence EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ (Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln) corresponds to INS(57-87) and is encoded by the human proinsulin gene (Steiner et al, 1967), where it is located between the two chains that subsequently form mature insulin. C-peptide plays a role in the proper folding of insulin, is cleaved from the propeptide to release mature insulin ... ... ... ...
 
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Entry last modified: September 2019