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CARD7

[caspase recruitment domain-containing protein-7] (see: CARD). This is another name for DEFCAP, NALP1, and NAC. The approved gene symbol for this protein is NLRP1 [NLR family, pyrin-domain containing 1].

The protein has been shown to be a component of a large, signal-induced multiprotein complex that has been termed inflammasome. For a viral counterpart of this protein see: KSHV orf63.

For other entries pertaining to cell death mechanisms see also the Apoptosis and Cell Death Dictionary section of this encyclopedia.

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