CD151 |
CD152L |
TPSYDTYAAELR |
||
[CD152(+), CD152(-)]
Other designations:
CTLA-4 [cytotoxic T-lymphocyte associated antigen 4]
The antigen is expressed upon cell activation on T-cells and B-cells. It is not expressed on resting T-cells.
Ling et al (1999) have reported the complete revised sequence of the human and mouse CTLA-4 genes.
CD152 is similar to the T-cell costimulatory CD28. Unlike CD28, CTLA-4 is an inhibitory receptor that functions as a major negative regulator of T-cell
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