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Corazonin

symbol: Crz. Corazonin is a peptide hormone, also termed Arg7-Corazonin, isolated from the American cockroach, Periplaneta americana (Veenstra, 1989). The sequence is Glu-Thr-Phe-Gln-Tyr-Ser-Arg-Gly-Trp-Thr-Asnamide; QTFQYSRGWTNamide) (note: the N-terminal amino acid is a pyroglutaminyl residue, pGlu) The name (Spanish for "heart") refers to the fact that the peptide was isolated from the corpora cardiaca. Corazonin is expressed in neurosecretory neurons of the pars lateralis of the protocerebrum and transported via nervi corporis cardiaci to the storage lobes of the corpora cardiaca.


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