Hippi

[Hip-1 protein interactor] The approved gene symbol is IFT57 [Intraflagellar transport protein 57 homolog]. A databank synonym, which is used in some publications, is ESRRBL1 [Estrogen-related receptor beta-like protein 1]

Hippi is a protein interactor and apoptosis co-mediator of Hip-1 [Huntingtin interacting protein 1], a protein that interacts with huntingtin, the expansion of which by polyglutamine leads to selective loss of neurons by an unknown mechanism causing cell death by apoptosis ... ... ... ...
 
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Entry last modified: February 2008