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Indian blood group antigen

[Indian blood group antigens]

abbr. In blood group antigen. This blood group antigen has been described originally by Badakere et al (1973, 1974) in the Indian population. The antigen is located on CD44 and exists in the form of two major alleles, designated In(A) (also: IN1) and In(B) (also: IN2) (Spring et al, 1988; Rao et al, 1994). Homozygosity for the In(A) allele is rare. Most individual express the In(B) variant. The polymorphism is caused by a single base change in exon 2 of CD44, which causes an Arg46 to pro substitution (Telen et al, 1996).

Poole et al (2007) have reported two further alleles, ... ... ... ... ... Subscribe to continue reading! ... ...


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