Leptin

approved gene symbol: LEP. Leptin is a secreted protein of 16 kDa (146 amino acids). The human leptin gene and murine obese gene (ob) are homologous (Zhang et al, 1994; Masuzaki et al, 1995; Ingalls et al, 1950). The gene product is being referred to also as obese protein or obesity factor. Human and murine leptin show approximately 84 % identity at the protein level. The human gene (20 kb; 3 exons) maps to chromosome 7q31.3 (Isse et al, 1995).

The circulating peptide ... ... ... ...
 
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Entry last modified: May 2012