SMDF

[Sensory and motor neuron-derived factor] This factor is expressed highly in sensory and motor neurons in human and rodent species. It is related to heregulin and appears to be identical with ARIA. The protein contains a C-terminal beta-type EGF-like repeat and a unique N-terminal sequence which lacks an Ig-like domain. Meyer et al (1997) have shown that SMDF is a splice variant of heregulin. Heregulin has been renamed neuregulin-1, and SMDF corresponds to a splice variant of neuregulin-1 type III, termed NRG1 type III-beta-3 ( ... ... ... ...
 
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Entry last modified: January 2013