TDAG8

[T-cell death-associated gene 8] This murine protein (337 amino acids) is identical with the G-protein-coupled receptor GPR65, which is also the approved gene symbol.

The expression of TDAG8 is increased during activation-induced cell death of T-cell in response to treatment with glucocorticoids or antibodies directed against the T-cell receptor (Choi et al, 1996; Kyaw et al, 1998).

Ishii et al (2005) have identified identified TDAG8 as a proton-sensing receptor that may play a role in immune response and cellular transformation under conditions accompanying tissue acidosis.

Im et al (2001) have identified TDAG8 as the psychosine receptor ... ... ... ... ... Subscribe to continue reading! ... ...