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TRAF interacting protein

abbr. TRIP. approved gene symbol TRAIP.

TRIP (469 amino acids) is a component of the apoptosis signaling complexes involving the TNF receptor and CD30 and the adaptor molecule TRAF (Lee et al, 1997). TRIP contains a RING finger motif and an extended coiled-coil domain. The protein is known also as RNF206 [RING finger protein 206].

TRIP mRNA levels are highest in mouse testis, thymus, and spleen and reduced in activated lymphocytes. TRIP associates with the TNFR2 or CD30 ... ... ... ... ... Subscribe to continue reading! ... ...

 

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