alpha-s1-casein(21-29) |
alpha-s1-casein(24-47) |
alpha-lactalbumin(50-52) |
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Also: casein-alpha-s1(23-34). This peptide with the sequence FFVAPFPEVFGK (Phe-Phe-Val-Ala-Pro-Phe-Pro-Glu-Val-Phe-Gly-Lys) is derived from bovine alpha-s1-casein (approved gene symbol: CSN1S1 [casein-alpha-s1]). It has been shown to act as an inhibitor of angiotensin-1 converting enzyme (CD143) and can lower blood pressure in rats (Karaki et al, 1990). See also: casokinins for peptides with similar activities.
The peptide is being referred to also as C12 Peptide and can lower blood pressure in hypertensive humans
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