gas-11

[Growth arrest-specific gene-11] gas-11 (approved gene symbol: GAS8 [Growth arrest-specific-8]) is one of the growth arrest-specific genes identified in quiescent, serum-starved NIH 3T3 mouse fibroblasts (see: gas genes).

Human and murine gas-11 proteins are 96 % identical. The human gene maps to chromosome 16q24.3 and may function as a tumor suppressor gene in human breast cancer. There are two different mRNAs expressed ubiquitously in heart and skeletal muscle. One transcript appears to be expressed in skeletal muscle alone (Whitmore et al, 1998).

The protein corresponds to DRC4 [ ... ... ... ...
 
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Entry last modified: January 2017