gas-5 |
GAS6-3T3 cells |
A7-1 |
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[Growth arrest-specific gene-6] gas-6 is one of the growth arrest-specific genes identified in quiescent, serum-starved NIH 3T3 mouse fibroblasts (see: gas genes) (Manfioletti et al, 1993).
gas-6 has been shown to be identical with Growth-potentiating factor (see: GPF), a 70 kDa factor released into the conditioned medium by growth-arrested rat vascular smooth muscle cells. This factor specifically potentiates vascular smooth muscle cells proliferation mediated by Calcium ion-mobilizing receptors.
A computer analysis of murine and human
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