ADAMTS19 |
ADAMTS21 |
Megakaryocyte growth and development factor |
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[a disintegrin and metalloproteinase with thrombospondin motif-20; ADAM metallopeptidase with thrombospondin type 1 motif 20] Human ADAMTS20 (1911 amino acids) is an ortholog of GON-1, an ADAMTS protease required for gonadal morphogenesis in Caenorhabditis elegans (Somerville et al, 2003). The secreted protein shows a domain organisation similar to that of other characterized members of the ADAMTS protein family. Expression is detectable in epithelial cells of the breast and lung and especially in testis. The gene is overexpressed in some human
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