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Ance

[Angiotensin-converting enzyme] Ance, called also Race (Tatei et al, 1995), is the Drosophila melanogaster ortholog of ACE [angiotensin-1 converting enzyme], encoded by gene CG8827 (Cornell et al, 1993, 1995). The enzyme converts angiotensin-1 to angiotensin-2, removes Phe-Arg from the C-terminus of bradykinin, and is inhibited by ACE inhibitors captopril and trandolaprilat.

Ance may play a role in the contractions of the heart, gut and testes, and in spermatid differentiation (Tatei et al, 1995; Hurst et al, 2003). Ance mutants die ... ... ... ... ... Subscribe to continue reading! ... ...

 

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