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Anoikis

Anoikis (detachment induced cell death or suspension induced apoptosis) is the name given to a special form of cell death by apoptosis. It was observed initially after disruption of the interactions between normal epithelial cells and extracellular matrix. In an intact organism anoikis ensures that cells are unable to survive in an inappropriate location. Anoikis thus is apoptosis caused by cell isolation or apoptosis of cells in suspension or, generally speaking, apoptosis caused by loss of adherence to substrate.

Detachment induced cell death can interfere with the establishment of long-term primary cultures of ... ... ... ... ... Subscribe to continue reading! ... ...

 

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