CD26 |
CD27 binding protein |
four-disulfide core domain |
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[CD27(+), CD27(-), CD27(-/+), CD27(+/-), CD27(hi), CD27(lo), CD27(high), CD27(low)]
This cell surface antigen is known also as 1A4, Tp55 (human), T14, or S152 (murine). Owing to its homology to other members of the TNF receptor superfamily the designation TNFRSF7 [TNF receptor superfamily member 7] is used also. The porcine ortholog has been identified as SWC2 [swine workshop cluster 2].
The human CD27 gene maps to chromosome 12p13. It encodes a transmembrane glycoprotein of 55 kDa (Tp55) which forms a disulfide-linked homodimer on resting
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