CD34
[CD34(+), CD34(-), CD34(+/-), CD34(high), CD34(low), CD34(bright), CD34(dim), CD34(low/-), CD34(int), CD34(-/lo), CD34(-/low)]
This cell surface antigen, formerly known as hemopoietic progenitor cell antigen 1 (HPCA1), is called also gp105-120. It is recognized by monoclonal antibodies BI.3C5, ICH3, MY10, 188.27 (see: HPCA1).
The human CD34 gene, which maps to chromosome 1q32, spans 26 kb and has 8 exons. CD34 is a 67 kDa transmembrane glycoprotein.
CD34 is expressed selectively on human hematopoietic progenitor cells. The biological function of CD34 is still unknown. It is used a surface marker for very early
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