CRTAM

[cytotoxic and regulatory T-cell molecule] The protein is being referred to also as Class-I MHC-restricted T-cell-associated molecule (Kennedy et al, (2000). In the nomenclature of CD antigens the receptor has been given the designation CD355.

CRTAM is a type 1 transmembrane protein with V and C1-like Ig domains (Yeh et al, 2008). Yeh et al (2008) have reported that CRTAM expression is upregulated in CD4(+) and CD8(+) T-cells. The human CRTAM cDNA has been cloned by Kennedy et al (2000). The deduced protein (393 amino acids shares 72 % amino acid identity with the mouse protein. Human CRTAM is expressed in ... ... ... ...
 
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Entry last modified: November 2010