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K562-IF

[K562 inhibitory factor] This biochemically uncharacterized factor of approximately 8 kDa is produced by the human erythroleukemic cell line K562. The factor inhibits adherence of human polymorphonuclear neutrophils and adherence-related functions in vitro. K562-IF also has potent anti-inflammatory activity in mice, associated with an inhibition of PMN functions (Amar et al, 1992).

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Entry last modified: January 2007

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