LMIF |
LMIR2 |
mitocryptide-ND5 |
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[leukocyte mono-Ig-like receptor 1] This receptor has been identified by Kumagai et al (2003). The extracellular domain of this receptor contains a single variable immunoglobulin (Ig) motif. The intracellular domain of LMIR1 contains several inhibitory ITIM motifs. When cross-linked, the intracellular domain is tyrosine phosphorylated and recruits tyrosine phosphatases, SHP-1 and SHP-2 and inositol polyphosphate 5-phosphatase, SHIP.
The receptor has been identified independently as CLM8 [CMRF35-like molecule-8], CMRF35H9 [CMRF35-like molecule H9] and IRp60 [inhibitory receptor protein 60].
In the
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