|COPE Homepage||Bottom of page||Previous entry:
family with sequence similarity 163 member A
please show your appreciation
by donating what you can afford.
[Macrophage-derived Apoptosis-Inducing RBCC protein] This RING-B-Box-coiled-coil (RBCC) protein consists of an N-terminal RING finger, followed by a B-Box zinc finger, a coiled-coil domain and a B30.2 domain. MAIR mRNA is expressed widely in mouse tissues. Its expression is induced by M-CSF in murine peritoneal and bone marrow macrophages. Ectopic expression of MAIR causes activation of caspase-7, caspase-8 and caspase-9 but not caspase-3, followed by apoptosis.
The cDNA has been cloned as KIAA1098. The gene has been identified independently as HLS5 [hemopoietic lineage switch 5]. The approved gene symbol is TRIM35 [tripartite motif-containing protein 35].
For other entries pertaining to cell death mechanisms see also the Apoptosis and Cell Death Dictionary section of this encyclopedia.
Copyright © 2012 by H IBELGAUFTS. All rights reserved.
ENTRY LAST MODIFIED: March 2011
See REFERENCES for entry MAIR.
Click BACKLINKS to see which COPE entries contain the term MAIR .
|COPE Homepage||Top of Page|
|SUPPORT COPE | Santa Claus | Intro | Subdictionaries | New Entries | Contribute data | COPE Credentials|
|COPE is looking for long-term support from a company appreciating and committed to communication biology|
| Access to COPE is free only for academic institutions and non-profit organizations. |
OTHER USERS: must contact COPE and pay a site licence fee.