NeoHep cells |
neokyotorphin(1-4) |
CCN family member 3 |
||
This peptide [TSKYR; Thr-Ser-Lys-Tyr-Arg] is derived from the C-terminus of the alpha-chain of hemoglobin (Takagi et al, 1982). It corresponds to HbA(137-141) [hemoglobin-alpha(137-141); alpha-hemoglobin(137-141)] that has been identified independently as having antibacterial activity (Nedjar-Arroume et al, 2006).
The peptide exhibits analgesic activity (Fukui et al, 1983) with a potency equal to that of Leu-Enkephalin (Kiso et al, 1983).
Zhu et al (1986) have isolated the peptide from a variety of lung carcinoma cells
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