Neuropoietin

abbr. NP; to avoid confusion see also: Neuropoietins. This protein is known also as cardiotrophin-2 (approved gene symbol: CTF2; abbr. also: CT-2).

The gene encoding murine neuropoietin has been identified by Derouet et al (2004). It is localized in tandem with the cardiotrophin-1 gene on mouse chromosome 7. Neuropoietin is structurally and functionally related with CNTF, cardiotrophin-1, and cardiotrophin-like cytokine. High expression of Neuropoietin is observed in embryonic neuroepithelial cells. Expression is seen also in the retina and, to a lesser extent, in skeletal muscle. In vitro, Neuropoietin is a survival factor ... ... ... ...
 
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Entry last modified: January 2013