Neuropoietin |
Neuropoietic cytokines |
gamma-GCT acting on glutathione homolog 1 |
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A generic name for factors known also as Neuropoietic cytokines or neurokines that regulate cell numbers in the nervous system and influence functional activities of neurons, for example, by determining the type of neurotransmitter used by certain neurons. Neuropoietins thus are important mediators within the Neuroimmune network and play a role in the control of neuronal, glial and immune responses to injury or disease.
These factors are not produced exclusively by brain cells and their activities are not restricted to these cell types. Factors with neuropoietic activity include CNTF (ciliary neuronotrophic factor), CDF (cholinergic differentiation factor
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