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Notch

The name of a gene (CG3936) in the genome of Drosophila melanogaster. The gene encodes a transcript of 10148 bp. Notch is an integral membrane protein of 2703 amino acids. Notch is the Drosophila melanogaster homolog of the human EGF receptor.

Mammals have more than one Notch gene homolog. Notch-1 (human chromosome 9q34) and Notch-2 (human chromosome 1p13-p11) are quite similar in structure while Notch-3 (human chromosome 19p13.2-p13.1) lacks some of the domains found in the other family members and encodes a considerably shorter ... ... ... ... ... Subscribe to continue reading! ... ...

 

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