PDCD9 |
PDCD11 |
primary cell cultures |
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(approved gene symbol) [programmed cell death-10] This protein is known also as murine TF1 cell apoptosis-related gene-15 (TFAR-15), identified initially through a screening for genes differentially expressed during the induction of cell death by apoptosis in the TF-1 premyeloid cell line.
Bergametti et al (2005) have identified the PDCD10 gene as the CCM3 [cerebral cavernous malformation 3] gene, mutations of which are responsible for cerebral cavernous malformations, a disorder characterized abnormally enlarged capillary cavities without intervening brain parenchyma.
Chen et al (2009) have reported that overexpression of wild-type PDCD10, but not disease-linked mutant forms, induce
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