PEDF

[pigment epithelium-derived factor] A protein of 50 kDa found to be secreted into the conditioned medium of pigment epithelial cells of the fetal human retina (Steele et al, 1992; Tombran-Tink et al, 1992). The protein is being referred to also as early population doubling level cDNA (EPC-1), identified originally as a cDNA the expression of which is upregulated strongly during cell cycle phase G0 in young but not in senescing cultured fibroblasts (Pignolo et al, 1995). PEDF has been identified independently as Caspin and SDF-3 [Stromal cell-derived factor-3].

PEDF exhibits approximately 27 % amino acid identity with ... ... ... ...
 
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Entry last modified: January 2022