Pref-1

[Pre-adipocyte factor-1] Pref-1 has been characterized as a transmembrane glycoprotein with six copies of an EGF-like repeat. Multiple pref-1 transcripts are generated by alternate splicing. In pre-adipocytes, multiple forms of the protein arise from various post-translational modifications (Smas and Sul, 1993; Smas et al, 1994). The protein has been described independently as pG2, FA-1 [Fetal antigen-1], and delta-like and sequence analysis has demonstrated that these proteins arise from the same gene (Lee et al, 1995).

Pref-1 mRNA is expressed abundantly in pre-adipocytes and its expression is abolished completely during differentiation of 3T3-L1 pre-adipocytes to adipocytes ... ... ... ...
 
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Entry last modified: August 2004