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Pregnant cells

[Pregnant cell]

This cell type has been described by Díaz-Carballo et al (2014) as a population of atypical cells associated with acquired resistance to cytostatic drugs and features of cancer stem cells. This morphological cell type is plasmodium-like and is said to be ubiquitous both in cell lines resistant to etoposide and in patient/xenograft material. These giant cells with a main giant nucleus are characterized by the presence of many daughter cells inside their cytoplasm, which is delimited by a common external membrane. The daughter cells appear to be capable of cell division and retain their own cytoplasmic membranes or acquire membrane material from the parental cell during eclosion (for comparison with ... ... ... ... ... Subscribe to continue reading! ... ...

 

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