RAF kinase inhibitor protein |
RAGLQFPVGRLLRRLLR |
ICH3 |
||
[receptor for advanced glycosylation end products] The approved gene symbol for this receptor is AGER [advanced glycosylation end product-specific receptor].
The gene on human chromosome 6p21.3 has been identified by Sugaya et al (1994). The receptor is a multiligand member of the immunoglobulin superfamily of cell surface molecules.
RAGE is the receptor for AGE (advanced glycosylation end product), a complex and heterogeneous group of compounds that are obtained as end products of a series of reactions involving the nonenzymatic glycosylation in vivo of cellular proteins, lipoproteins, or nucleic acids. Thus, RAGE is a pattern recognition receptor that binds multiple ligands derived from a damaged cell environment.
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |
| SUPPORT COPE | Intro | Subdictionaries | New Entries | Contribute data | COPE Credentials |
| # | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z |
|
Created, developed, and maintained by Dr H Ibelgaufts
|
U L T R A P O S S E N E M O O B L I G A T U R