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S100A14

[S100 calcium binding protein A14] This is a calcium-binding protein related to the S100 family of proteins. It is known also as BCMP84 [breast cancer membrane protein 84] (Adam et al, 2003). S100A14 is expressed widely and appears to be overexpressed in some cancers (ovary, breast, uterus) and underexpressed in other cancers (kidney, rectum, colon) (Pietas et al, 2002, Adam et al, 2003).

Sapkota et al (2012) have shown that S100A14 overexpression induces G1-arrest in oral squamous cell carcinoma cells. Sapkota et al (2011) have shown that S100A14 over-expression is associated with down-regulation of MMP-1 and MMP-9 in oral squamous cell carcinoma cell lines ... ... ... ... ... Subscribe to continue reading! ... ...

 

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