TCA-3

[T-cell activation-3] This factor is produced by T-cells after cell activation (Burd et al, 1987). It is expressed selectively during activation via the antigen-receptor pathway or stimulation of the cells by concanavalin A. Expression of TCA-3 in response to Con A is blocked by cyclosporin A treatment (Wilson et al, 1990). The factor is produced also by mast cells (Oh and Metcalfe, 1994).

TCA-3 belongs to the family of chemotactic cytokines known as Chemokines. It is the murine homolog of human I-309 (Luo et al, 1993). The gene which contains at least three introns and has a length less than 4.7 kb maps to murine ... ... ... ...
 
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Entry last modified: January 2004