wntD |
Wnt family member 1 |
Gln-Leu-Gln-Ser-Asn-Gly-Glu-Pro-Ala-Tyr-Arg-Val-Arg-Thr-Pro-Arg-Leuamide |
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[Wnt protein, Wnt proteins]
[wingless-type MMTV integration site proteins] The designation "Wnt" is an acronym coined from the Drosophila melanogaster wingless gene, which is the Drosophila homolog of int-1, identified originally as a chromosomal site of insertion of mouse mammary tumor virus (MMTV) on mouse chromosome 15. Wnt genes are structurally related genes that encode cysteine-rich secreted glycoproteins associated with the extracellular matrix of cells. All mammalian Wnt proteins are secreted proteins with a length of approximately 350-400 amino acids. They contain a large conserved domain
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