aBCGF

[Autostimulatory B-cell growth factor] abbr. also: aBGF. This biochemically uncharacterized factor of 16 kDa is secreted constitutively into the conditioned medium of Epstein-Barr virus-transformed human cell line derived from B-cells. It exists as monomeric dimeric, and tetrameric forms. aBCGF acts as in an autocrine manner for Epstein-Barr virus-transformed B-cells.

aBCGF is not identical with IL1 or IL6 that have been described also to possess growth-promoting activity for Epstein-Barr virus-transformed B-cells.

See also: BCGF (B-cell growth factors). For ... ... ... ...
 
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Entry last modified: March 2011