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dActivin

[Drosophila Activin; abbr. dAct] dActivin is encoded by the CG11062 gene and encodes the Drosophila ortholog of Activin-beta (Inhibin-beta) (Kutty et al, 1998; Haerry and O'Connor, 2002). The factor acts through the Babo receptor and controls several aspects of neuronal morphogenesis during development (Zheng et al, 2003; Zhu et al, 2008; Ting et al, 2007). Sander et al (2010) have implicated dActivin signaling involving the SMAD protein dSmad2 in Drosophila wing development, where it antagonizes dpp and Mad signaling.

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